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Tadalista does not increase sexual desire and does not automatically cause an erection. Sexual stimulation is necessary for the medicine to work. Tadalafil has a relatively long duration of action compared with some other ED medicines, which may provide greater flexibility around the timing of sexual activity. The appropriate dose depends on individual health factors, other medications, and how a person responds to treatment. Common side effects can include headache, indigestion, flushing, nasal congestion, back pain, muscle aches, and dizziness.